
Loads the data from species and populations and analyzes their DNA sequence. Displays graphs, DNA sequence data and all the necessary information to obtain a complete analysis. Includes various sequence analysis (phylogeny inference, model selection, dating and clocks, ancestral states, etc) as well as statistical methods (maximum likelihood, distance methods, ordinary least squares, parsimony, Bayesian and more).
MEGA is an integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web-based databases, estimating rates of molecular evolution, inferring ancestral sequences, and testing evolutionary hypotheses.
MEGA is a multi-threaded Windows application. It runs on all releases of Microsoft Windows operating system.
v5.1 [Jul 31, 2012]
Sped up ML bootstrap tree construction (by avoiding likelihood computation at non-resampled sites).
Added TBR (Tree Bisection Reconnection) and SPR (Subtree Pruning Regrafting) search heuristics for MP phylogeny reconstruction.
Removed CNI (Close Neighbor Interchange) search heuristic from MP phylogeny reconstruction.
Replaced slow TIFF image export with PNG export (similar format, lossless, widely used).
Fixed a critical calculation bug which occured in some cases where bootstrapping wasn't resampled correctly (only was an issue with ML trees). This bug only ever existed in the beta.